Bazı soğansı bitkilerin antioksidan aktivitelerinin belirlenmesi

06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.Meyve ve sebzelerde doğal olarak bulunan fenolik yapılı bileşikler (flavonoidler, polifenoller), antioksidan özellik göstermekte ve birçok hastalığa iyi geldiği bilinmektedir. Fenolik bileşiklere ilaveten kronik hastalıklara karşı koruyucu yapıdaki kimyasal maddeler karotenoidler, askorbik asit (C vitamini), tiyoller ve tokoferollerdir.Soğanlı bitkilerin flavonoidli yapıları yüksek antioksidan aktiviteye sahip olduğunu gösterir. Soğanlı bitkiler ile beslenerek alınan flavonoidlerin metabolizmadaki işlevi; kanser, kalp ve kronik rahatsızlıkları azaltmak şeklindedir.Soğansı bitkilerin bu fonksiyonları büyük önem teşkil ettiğinden bu konuda bir çalışma tercih edilmiştir. Bu çalışmada kurutulmuş "Allium" bitkilerinden olan pırasa (Allium Porrum L.) ile yeşil soğan (Allium Cepa L.) bitkilerinin ve sarı zambak olarak da bilinen bir soğangil olan çirişin (Asphodelus Ramosus) antioksidan aktiviteleri çeşitli metodlarla incelenmiştir. Bu amaçla bitkiler etüvde farklı sıcaklıklarda kurutulup, doğrayıcı ile ufak parçalar haline getirildikten sonra su, metanol ve etil asetat çözülüleri ile ekstrakte edilmiş, bu sayede bitkilerin antioksidan aktivitelerini belirlemede sıcaklık ve çözücü olarak iki parametre kullanılmıştır.Antioksidan kapasiteye neden olan türlerin belirlenmesi amacıyla, her ekstraktın Folin Cioceltau reaktifi ile toplam fenolik madde içeriği, alüminyum nitrat yöntemi ile toplam flavonoid madde miktarı, DPPH üzerinden serbest redikal süpürücü etki tayini, H2O2 giderme aktivite tayini, bakır (II) iyonu indirgeyici antioksidan kapasite tayini (CUPRAC), süperoksit anyon radikali giderim aktivitesi tayini yapılmıştır ve bunlar HPLC (Yüksek Performanslı Sıvı Kromotografisi) ile desteklenmiştir.Structure of phenolic compounds found naturally in fruits and vegetables (flavonoids, polyphenols), show antioxidant properties and is known to be good for many diseases. Phenolic compounds protect against chronic diseases in addition to the structure of chemical substances carotenoids, ascorbic acid (vitamin C), thiols and tocopherols.Plants of onion which have flavonoid structure indicate that the high antioxidant activity. The functions in metabolism of flavonoids which have taken with onions of plants is to reduce cancer, heart and chronic diseases.A study on this issue was chosen because of crucial functions of these plants. In this study, the leek (Allium Porrum L.) dried "Allium" plants and green onion (Allium Cepa L.) and Asphodelus Ramosus also known as a yellow lily which has been a plant of onion were investigated about antioxidant activities with various methods. For this purpose, plants dried in the oven at different temperatures, were chapped into small pieces with a blender after that the plants were extracted with water, methanol and ethyl acetate resolution, so that the antioxidant activity of plants were determined for two parameters as temperature and solvent.In order to determine the antioxidant capacity of the species, all of the extracts were analyzed with various methods which those; total phenolic content with Folin Cioceltau reagent, total flavonoid content with aluminum nitrate method, DPPH free redical scavenging through the determination, the determination of the activity of removal of H2O2, copper (II) ion reducing antioxidant capacity determination (CUPRAC), removal activity of super oxide anion and the resulrs were with HPLC (High Performance Liquid Chromatography)

Hamile kadınlarda COVID-19 pandemisinin depresyon, anksiyete ve stres düzeyleri üzerine etkisi

Objective: Coronavirus disease-2019 (COVID-19) pandemic has negatively affected the psychology of the society. In this study, it was aimed to determine the stress, anxiety and depression levels in pregnant women during the COVID-19 pandemic and to investigate the delivery method attitudes using various scales. Method: The study included 151 pregnant women admitted to the obstetrics and gynecology clinic of our tertiary hospital for follow-up. A 31-question questionnaire containing demographic information and questions about COVID-19, impact of event scale (IES-R), depression anxiety stress scale-21 (DASS-21) and revised pregnancy-related anxiety questionnaire-revised (PRAQ-R) scales were applied. Results: According to the classifications made in DASS-21 subgroups, 16.5% of the pregnant women had severe or extreme depression, 35.1% had severe or extreme anxiety, 11.2% had severe or extreme stress level. The mean IES-R and PRAQ-R scores were found to be significantly higher in those under 35 years of age than those aged 35 years and over (p=0.02 and p=0.01, respectively). PRAQ-R (p<0.001), DASS-21 total (p=0.019), DASS-21 anxiety (p=0.012) and DASS-21 stress (p=0.014) scores were significantly higher in those who had their first pregnancy compared to experienced pregnant women. Conclusion: In the present study, it was determined that the pandemic had a negative effect on the depression, anxiety and stress levels of pregnant women, and this effect was higher especially in younger pregnant women and in those experiencing their first pregnancy.Amaç: Koronavirüs hastalığı-2019 (COVID-19) salgını toplumun psikolojisini olumsuz etkilemiştir. Bu çalışmada, gebelerde COVID-19 salgını sırasında yaşanan stres, anksiyete ve depresyon düzeylerinin belirlenmesi ve çeşitli ölçeklerle doğum yöntemi tutumlarının incelenmesi amaçlanmıştır. Yöntem: Çalışmaya üçüncü basamak hastanemizin kadın hastalıkları ve doğum kliniğine takip için başvuran 151 gebe dahil edildi. Gebelerin hepsine demografik bilgilerini içeren ve COVID-19, olay etkisi ölçeği (IES-R), depresyon anksiyetesi stres ölçeği-21 (DASS-21) ve gözden geçirilmiş gebelikle ilgili anksiyete anketi (PRAQ-R) ile ilgili soruları içeren 31 soruluk bir anket uygulandı. Bulgular: DASS-21 alt gruplarında yapılan sınıflandırmalara göre, gebelerin %16,5’i şiddetli veya aşırı depresyon, %35,1’i şiddetli veya aşırı anksiyete, %11,2’si şiddetli veya aşırı stres düzeyine sahipti. Otuz beş yaşın altındakilerde ortalama IES-R ve PRAQ-R puanları 35 yaş ve üzerindekilere göre anlamlı derecede yüksek bulundu (sırasıyla p=0,02 ve p=0,01). İlk defa hamile olanlarda PRAQ-R (p<0,001), DASS-21 toplam (p=0,019), DASS-21 anksiyete (p=0,012) ve DASS-21 stres (p=0,014) puanları daha önce gebelik geçiren kadınlara göre yüksekti. Sonuç: Bu çalışmada, salgının gebelerin depresyon, anksiyete ve stres düzeylerini olumsuz etkilediği, bu etkinin özellikle genç gebelerde ve ilk gebeliğini yaşayanlarda daha da yüksek olduğu tespit edilmiştir

Keystones of Performing a Proper Tax Policy Design for Tax Compliance: Does Perception of Tax Compliance Develop in Persons Who Are Not Tax Payers Yet?

Tax compliance takes place in the scope of the efficiency of the tax implementation. Tax income operations are heavily dependent on tax compliance, while the fairness of the allocation of tax burden affects the tax payers’ compliance. The situation has been studied here by dealing with university students in regard to whether or not a perception of tax compliance develops in highly educated people who are not tax payers yet and to what degree. The findings of the study briefly states that students agree that paying taxes completes the concept of being a good citizen, perceive the sensitivity submitting declarations on time and showing care in paying tax debts, and have negative perceptions on the tax administration being transparent, correct, and trustable. So for, an achievement of a proper tax policy design should be primarily considered as the perception of tax compliance of the people, who being the tax payers of any country

Molecular basis for solvent dependent morphologies observed on electrosprayed surfaces

We study the causes of the observed tunable hydrophobicity of poly(styrene-co-perfluoroalkyl ethylacrylate) electrosprayed in THF, DMF, and THF : DMF (1 : 1) solvents. Under the assumption that equilibrium morphologies in the solvent significantly affect the patterns observed on electrosprayed surfaces, we use atomistic and coarse-grained simulations supported by dynamic light scattering (DLS) experiments to focus on the parameters that affect the resulting morphology of superhydrophobic electrosprayed beads. The differing equilibrium chain size distributions in these solvents examined by DLS are corroborated by chain dimensions obtained via molecular dynamics simulations. Mesoscopic morphologies monitored by dissipative particle dynamics simulations explain experimental observations; in particular, the preference of the polymer for THF over DMF in the binary mixture rationalizes the dual scale roughness driven by stable microphase separation. Drying phenomena that affect resultant dual-scale roughness are described in three stages, each interpreted by concentration dependent diffusion and surface mass transfer coefficients of the solvents. Irrespective of the presence of polar groups in the structure, a conflict between the lower-boiling point solvent adhering to the polymer and the less volatile solvent abundant in the bulk leads to perfectly hydrophobic surfaces

The Effects of Reduction Mammaplasty on Body Perception, Quality of Life and Depression in Women with Symptomatic Macromastia

AimThe aim of the present study is to examine the effects of reduction mammaplasty on body perception, quality of life and depression levels in women with symptomatic macromastia.Materials and MethodsThis study included 45 patients with symptomatic macromastia. Quality of life, body perception and depression levels compared before and 6 months after reduction mammaplasty. The Information Form, the SF-36 Quality of Life Form, Body Perception Scale Form, and the Beck Depression Inventory (BDI) were administered to the patients.ResultsThe mean participant age was 41,020 ± 11,526 (range 18–61 years). The mean total weight of the specimens resected from both breasts 2808,890 ± 559,859 gr. Patients preoperative BMI ranged from 24.51 to 46.88 kg/m2, with a mean of. 35,030±5,376 kg/m2. Postoperative BMI ranged from 23.80 to 44.53 kg/m2, with a mean of 33,320±5,083 kg/m2. Compared to preoperative scores, we found significant improvements in SF-36 quality of life scores, body perception scores and depression levels conducted in the sixth month after the surgery (p<0,05).ConclusionOur study has shown that quality of life, body perception and depression was improved after reduction mammaplsty in women with symptomatic macromastia

Avanos kırmızı çömlek bünyesine uygulanan sırlarda renk oluşumlarının incelenmesi

Farklı reçetelerdeki seramik çamur bünyeler üzerine uygulanan sırlar, çamurun içinde bulunan hammaddelerin özelliklerinden dolayı reaksiyonlar gösterebilmektedir. Pişme derecesi, pişirim teknikleri, fırın atmosferi ve daha pek çok etken sırlarda çeşitli reaksiyonlara neden olabilmektedir. Bunlar arasında, sırın bünyeye tutunması, bor tülü oluşumu, akışkanlık durumu, renk özelliklerinde farklılıklar gibi örnekler verilebilir. Araştırma kapsamında, Avanos bölgesine ait iki ayrı kırmızı çömlek çamuru seçilerek bisküvi pişirimlerinin ardından uygulanan sırların renkleri ölçülmüştür. Çalışmada, üç farklı kompozisyon hazırlanarak 1350ºC’de ergitilmiş ve suda şoklanarak firitler elde edilmiştir. Öğütülme aşamasından sonra sırlar bünyeler üzerine uygulanarak 1000ºC’de pişirilmiştir. Ürünlerin kromatik koordinatları (L*, a*, b*) Minolta CM-3600d renk ölçüm cihazı ile yapılmış ve elde edilen renk değerleri kıyaslanmıştır. Deney plakaları dışında, aynı kil bünyelerden artistik formlar şekillendirilerek dokulu yüzeylerdeki etkileri gözlemlenmiştir

Comparison of active vs. expectant management of the third stage of labor in women with low risk of postpartum hemorrhage: a randomized controlled trial

Objectives: To compare the ‘strictly’ active management protocol in women with low risk of postpartum hemorrhage using the expectant management protocol with respect to changes in hematologic parameters, uterotonics, blood transfusions, or additional interventions. Material and methods: A randomized controlled prospective trial in which 934 singleton parturients enrolled; 654 were randomly assigned to the active and mixed management groups. The primary outcome parameter was the reduction in hemoglobin concentrations due to delivery, and the secondary outcome parameters were changes in hemoglobin of more than 3 g/dL (ΔHb ≥ 3 g/dL), durations of the third stage of labor, need for additional uterotonic agents, blood transfusions, manual removal of the placenta, and surgical evacuation of retained products of conception. Results: The mean postpartum hemoglobin concentration was significantly higher (P = 0.04) in the active management group with a significantly lower reduction (P = 0.03). Falls of hemoglobin levels of more than 3 g/dL (ΔHb ≥ 3g/dL) were less common in the active management group though not significantly (P = 0.32). The mean duration of the third stage of labor was significantly (P &lt; 0.001) shorter in the active management group. There was no significant difference between the two groups with regard to the need for additional uterotonic agents, uterine atony, blood transfusion, manual removal of the placenta, surgical evacuation of retained products of conception, and prolonged third stage of labor. Conclusions: Although active management of the third stage of labor was associated with higher postpartum hemoglobin levels, it did not influence the risk of ‘severe postpartum hemorrhage’ in women with low risk of postpartum hemorrhage

Predictive Factors of Complications and Visual Outcomes after Pediatric Cataract Surgery: A Single Referral Center Study from Türkiye

Objectives:To evaluate the predictive factors of complications and visual acuity outcomes in pediatric cataract patients.Materials and Methods:This retrospective, observational clinical study included 80 eyes of 50 patients treated for pediatric cataracts between 2010 and 2020. The eyes were divided into Group I (congenital cataracts, n=38) and Group II (developmental cataracts, n=42). Group II was also divided into Group IIA (aphakic, n=21) and Group IIB (pseudophakic, n=21). The effects of the age, laterality, cataract morphology, intraocular lens implantation, preoperative nystagmus/strabismus, and intraoperative anterior hyaloid rupture on complications and final best-corrected visual acuity (BCVA; logMAR) were evaluated.Results:The median (interquartile range) age and follow-up time were 28 (5-79) months and 60 (29-84) months, respectively. There was a significant difference in mean final BCVA between Group I (0.79±0.46) and Group II (0.57±0.51) (p=0.047); however, no difference was observed between Group IIA and Group IIB (p=0.541). Having congenital cataract (p=0.045), preoperative nystagmus/strabismus (p=0.042), total/mature cataract (p<0.001), and postoperative complications (p=0.07) were significantly associated with final BCVA. However, in multivariate analysis, only total/mature cataract (β: 0.52, p<0.001) and having any complication (β: 0.24, p=0.018) were associated with final BCVA. Congenital cataract and intraoperative anterior hyaloid rupture were the only significant risk factors of postoperative complications on univariate (p=0.027 and p=0.003, respectively) and binary logistic regression analysis (odds ratio [OR]: 2.95 [95% confidence interval: 1.07-8.15], p=0.036 and OR: 4.28 [95% confidence interval: 1.55-11.77], p=0.005, respectively).Conclusion:Total/mature cataract and the presence of any postoperative complication adversely affected the final BCVA. Having a congenital cataract and intraoperative anterior hyaloid membrane rupture increased the risk of complications